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Hyaluronidase is a virulence factor in ______.


A) amoebic dysentery
B) ringworm
C) clostridia
D) cold virus
E) diphtheria

F) A) and E)
G) All of the above

Correct Answer

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An infectious agent that originates from outside the body is called ______.


A) exogenous
B) an exotoxin
C) an enterotoxin
D) endogenous
E) axenic

F) C) and E)
G) D) and E)

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Which genus is the most common resident biota of mouth surfaces?


A) Lactobacillus
B) Streptococcus
C) Haemophilus
D) Escherichia
E) Mycobacterium

F) All of the above
G) D) and E)

Correct Answer

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Keratinase has the greatest effect on the ______.


A) respiratory system
B) gastrointestinal system
C) urinary system
D) genital system
E) skin

F) C) and D)
G) A) and B)

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The primary, natural habitat of a pathogen where it continues to exist is called the ______.


A) fomite
B) carrier
C) vector
D) reservoir
E) source

F) A) and E)
G) A) and D)

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An endotoxin is ______.


A) secreted by pathogenic organisms
B) indicative of gram-negative bacterial infection
C) secreted by gram-positive organisms
D) indicative of fungal infections
E) indicative of viral infections

F) C) and D)
G) B) and E)

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The principal government agency responsible for tracking infectious diseases in the United States is the _______.


A) Centers for Disease Control and Prevention
B) World Health Organization
C) National Institutes of Health
D) United States Department of Agriculture
E) Infection Control Committee

F) B) and C)
G) A) and B)

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The infectious doses for various bacterial infections are listed in the table below. Which of these bacteria would likely have the greatest virulence?  Bacterium  Infectious Dose (ID)   Mycobacterium tuberculosis 10 Neisseria gonorrhoeae 1,000 Vibrio cholerae 1,000,000,000 Salmonella enterica 10,000\begin{array} { | | l | | l | | } \hline { \text { Bacterium } } &{ \text { Infectious Dose (ID) } } \\\hline \hline \text { Mycobacterium tuberculosis } & 10 \\\hline \hline \text { Neisseria gonorrhoeae } & 1,000 \\\hline \hline \text { Vibrio cholerae } & 1,000,000,000 \\\hline \hline \text { Salmonella enterica } & 10,000 \\\hline \hline\end{array}


A) Vibrio cholerae
B) Neisseria gonorrhoeae
C) Salmonella enterica
D) Mycobacterium tuberculosis

E) A) and B)
F) A) and C)

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Virulence factors include all of the following except ______.


A) capsules
B) ribosome
C) exoenzymes
D) endotoxin
E) exotoxin

F) A) and C)
G) C) and D)

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Virulence refers to the degree of pathogenicity manifested by a microbe, not simply whether or not it causes disease.

A) True
B) False

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The skin's resident biota are localized to only the outermost superficial layer of the epidermis.

A) True
B) False

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Under certain circumstances, a person's resident biota can act as opportunistic pathogens.

A) True
B) False

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An infectious agent already existing on or in the body is called ______.


A) exogenous
B) an exotoxin
C) an enterotoxin
D) endogenous
E) axenic

F) B) and C)
G) A) and D)

Correct Answer

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Which of the following is not true of the preliminary findings by the HMP thus far?


A) The number of bacterial genes outnumber human genes by millions in the holobiont
B) There are many more sterile sites in the human than were previously assumed
C) Microbial antagonism prevents potential pathogens in the resident biota from causing disease
D) Viruses have played an important role in guiding the evolution of both humans and their resident flora

E) A) and D)
F) C) and D)

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Which of the following is not true regarding healthcare-associated infections?


A) These infections are only transmitted by medical personnel.
B) These infections often involve the patient's urinary tract and surgical incisions.
C) The patient's resident biota can be the infectious agent.
D) Escherichia coli and staphylococci are common infectious agents.
E) Medical and surgical asepsis help lower their occurrence.

F) A) and E)
G) A) and D)

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The virulence factors of a pathogen are determined by how strong or weak a patient's body defenses are at the time of infection.

A) True
B) False

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The minimum number of microbes required for infection to proceed is termed a/an ______.


A) virulence factor
B) indigenous biota
C) infectious dose
D) endotoxin
E) minimal dose

F) A) and B)
G) None of the above

Correct Answer

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Reservoirs include ______.


A) humans
B) animals
C) soil
D) water
E) All of the choices are correct.

F) B) and E)
G) A) and D)

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A disease that has a steady frequency over time in a particular geographic location is referred to as ______.


A) epidemic
B) endemic
C) pandemic
D) sporadic
E) chronic

F) C) and E)
G) B) and E)

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The prevalence rate of tuberculosis in one particular county in Texas is 7/1000 people, while the incidence rate for 2011 is 2/1000 people. Analyze this data and summarize the situation.


A) The data were collected incorrectly because the two values should match.
B) Incidence rate should really be higher than prevalence rate because it includes all new cases for the year.
C) Prevalence rate is higher than incidence rate because the number of people still alive with tuberculosis is higher because of better treatments.
D) Prevalence rate and incidence rate cannot be determined for the same disease.

E) B) and C)
F) All of the above

Correct Answer

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