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Salts in solution separate into positively and negatively charged


A) membrane potentials.
B) EPSPs.
C) IPSPs.
D) ions.
E) crystals.

F) B) and E)
G) A) and D)

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Outside the membranes of resting neurons, there are many more


A) inhibitory neurotransmitters.
B) neurotransmitters.
C) Na+ ions.
D) K+ ions.
E) nuclei.

F) C) and D)
G) B) and D)

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Recent technological developments have led to the discovery of __________ throughout the mammalian brain; they seem to link the activities of inhibitory interneurons of the same type.


A) neuropeptides
B) gap junctions
C) multipolar neurons
D) chemical synapses
E) G-proteins

F) B) and D)
G) C) and D)

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The drug, __________ , is a muscarinic antagonist and pupil dilator.

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Describe and explain how four ionic events contribute to the typical action potential-to help organize your answer label the four arrows in this illustration with the associated ionic event. Describe and explain how four ionic events contribute to the typical action potential-to help organize your answer label the four arrows in this illustration with the associated ionic event.

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This drug is a muscarinic acetylcholine antagonist; it is an extract of the belladonna plant; and it has pupil-dilating effects:


A) atropine.
B) curare.
C) morphine.
D) opium.
E) Librium.

F) B) and D)
G) B) and C)

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A neuron normally fires when


A) its sodium-potassium pumps are stimulated.
B) there is an EPSP.
C) there is an IPSP.
D) the degree of depolarization on the axon adjacent to the hillock exceeds the threshold of excitation.
E) its buttons are stimulated.

F) C) and D)
G) A) and C)

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Many neurons contain and release two neurotransmitters. This situation is called


A) covalence.
B) ionotropism.
C) cohabitation.
D) metabotropism.
E) coexistence.

F) None of the above
G) C) and D)

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Contributing to the unequal distribution of ions on either side of a resting neural membrane


A) is random ion movement.
B) are electrostatic gradients.
C) are sodium-potassium pumps.
D) both A and B
E) both B and C

F) A) and E)
G) C) and D)

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About how many neuropeptides are currently classified by most experts as neurotransmitters?


A) 2
B) 4
C) 9
D) just over 100
E) almost 3,000

F) A) and C)
G) A) and D)

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Peptide neurotransmitters (i.e., neuropeptides) are synthesized in the cell body and


A) stored in the Golgi complex until they are broken down.
B) released by the Golgi complex into the synapse.
C) transported in vesicles along microtubules to the buttons.
D) stored in ribosomes with small-molecule neurotransmitters.
E) transported along the axons to the nodes of Ranvier.

F) A) and C)
G) A) and B)

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The most prevalent inhibitory neurotransmitter in the mammalian brain is __________.

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The first event in the generation of an action potential is the opening of __________- activated sodium channels.

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Many buttons contain two sizes of vesicles; the larger ones typically contain


A) small-molecule neurotransmitters.
B) neuropeptides.
C) acetylcholine.
D) dopamine.
E) glutamate.

F) C) and D)
G) A) and B)

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Which of the following is not found in neurons that release norepinephrine?


A) dopamine
B) L-DOPA
C) norepinephrine
D) epinephrine
E) tyrosine

F) C) and D)
G) B) and C)

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Metabotropic receptors are associated with signal proteins in the cell membrane of the postsynaptic neuron and with __________ that are attached to the signal protein inside the neuron.

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Drugs that degrade vesicles and cause the neurotransmitter molecules to leak into the cytoplasm, where they are destroyed by enzymes, are


A) receptor blockers.
B) agonists of the neurotransmitter.
C) antagonists of the neurotransmitter.
D) autoreceptor blockers.
E) amino acids.

F) A) and B)
G) A) and E)

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The wave of absolute refractoriness that follows an action potential


A) keeps the action potential from spreading actively back along an axon towards the cell body.
B) increases the firing rate.
C) increases the speed of axonal transmission.
D) produces a second, negative action potential.
E) produces saltatory conduction.

F) A) and B)
G) A) and C)

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Glycine, aspartate, and glutamate are


A) amino acid neurotransmitters.
B) small-molecule neurotransmitters.
C) transmitters at fast-acting, directed synapses.
D) building blocks of proteins.
E) all of the above

F) B) and D)
G) B) and E)

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Drugs that increase the activity of a particular neurotransmitter are said to be __________ of that neurotransmitter.

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